Organisers and Genes (1940), by Conrad Hal Waddington
نویسنده
چکیده
Conrad Hal Waddington?s Organisers and Genes [4], published in 1940, is a summary of available research and theoretical framework for many concepts related to tissue differentiation [5] in the developing embryo. The book is composed of two main conceptual sections. The first section explores the action and nature of the organizer [6], while the second section delves into genes [7] and their influence on development.
منابع مشابه
"Experiments on Embryonic Induction III. A Note on Inductions by Chick Primitive Streak Transplanted to the Rabbit Embryo" (1934), by Conrad Hal Waddington
Conrad Hal Waddington?s ?Experiments on Embryonic Induction III,? published in 1934 in the Journal of Experimental Biology, describes the discovery that the primitive streak [7] induces the mammalian embryo. Waddington?s hypothesis was that a transplanted primitive streak [7] could induce neural tissue in the ectoderm [8] of the rabbit [9] embryo. The primitive streak [7] defines the axis of an...
متن کامل"Experiments on the Development of Chick and Duck Embryos, Cultivated in vitro" (1932), by Conrad Hal Waddington
Conrad Hal Waddington?s ?Experiments on the Development of Chick and Duck Embryos, Cultivated in vitro [5],? published in 1932 in Philosophical Transactions of the Royal Society of London, Series B, compares the differences in the development of birds [6] and amphibians [7]. Previous experiments focused on the self differentiation [8] of individual tissues in birds [6], but Waddington wanted to...
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The epigenetic landscape [2] is a concept representing embryonic development. It was proposed by Conrad Hal Waddington [3] to illustrate the various developmental pathways a cell might take toward differentiation [4]. The epigenetic landscape [2] integrates the connected concepts of competence [5], induction [6], and regulative abilities of the genes [7] into a single model designed to explain ...
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Introduced by Conrad Hal Waddington [3] in 1942, the concept of epigenetics [4] gave scientists a new paradigm of thought concerning embryonic development, and since then has been widely applied, for instance to inheritable diseases, molecular technologies, and indeed the human genome [5] as a whole. A genome [5] contains an embedded intricate coding template that provides a means of genetic ex...
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